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Blog > Why is Sildigra 250 Mg considered a PDE5 ?
Why is Sildigra 250 Mg  considered a PDE5 ?
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kirazmattson
351 posts
Nov 11, 2024
12:43 AM
Sildigra 250 mg is considered a PDE5 inhibitor because its active ingredient, Sildenafil, works by blocking the action of the phosphodiesterase type 5 (PDE5) enzyme. The PDE5 enzyme is primarily responsible for breaking down cyclic GMP (cGMP) in the smooth muscle cells of the penis. When a man is sexually aroused, the body releases nitric oxide, which stimulates the production of cGMP. This molecule helps relax the smooth muscles in the blood vessels of the penis, allowing for increased blood flow and Sildigra 250 in an erection. However, PDE5 breaks down cGMP, which can limit or stop the erection process. By inhibiting PDE5, Sildigra 250 mg helps increase the levels of cGMP, enhancing the relaxation of blood vessels and improving blood flow to the penis, leading to a stronger and longer-lasting erection during sexual activity. This mechanism is the same as other PDE5 inhibitors, such as Viagra, which also uses sildenafil as its active ingredient but in lower doses.
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